Mytomicin-C, cisplatin and fluorouracil for advanced/recurrent head and neck squamous carcinoma. A preliminary report
โ Scribed by Cartel, G.; Lop, A.; Clocchiatti, L.; Sibau, A.; Mansutti, M.; Vigevani, E.
- Book ID
- 123301192
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 128 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0753-3322
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Patients with locally advanced, inoperable squamous cell carcinoma of the head and neck were offered three courses of cisplatin and 96-h 5-fluorouracil (5-FU) infusion. Subsequent therapy included surgery when feasible, irradiation therapy, and a maintenance program of methotrexate (MTX)-5-FU. Thirt
## BACKGROUND. The combination of cisplatin and 5-flurouracil (5-FU) is considered standard therapy for patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN). Paclitaxel has exhibited single-agent activity in patients with this disease. The authors conducted thi