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Myorelaxant and antispasmodic effects of the essential oil of Alpinia speciosa on rat ileum

✍ Scribed by Maria A. C. Bezerra; José H. Leal-Cardoso; Andrelina N. Coelho-de-Souza; David Neil Criddle; Manassés C. Fonteles

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
51 KB
Volume
14
Category
Article
ISSN
0951-418X

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✦ Synopsis

The effects of the essential oil of Alpinia speciosa Schum (EOAS) on rat ileum were studied. EOAS (0.1-600 mg/mL) reversibly relaxed ileal basal tonus. Submaximal contractions induced by 60 mM KCl or acetylcholine were concentration dependently inhibited by EOAS with similar IC 50 values ($ 44 and 48 mg/mL, respectively). These results show that EOAS possesses both relaxant and antispasmodic actions in the ileum.

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