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Myocardiotoxicity of 5 Fluorouracil

✍ Scribed by B. Coronel; O. Madonna; A. Mercatello; A. Caillette; J. F. Moskovtchenko

Publisher: Springer
Year: 1988
Tongue: English
Weight: 123 KB
Volume: 14
Category: Article
ISSN: 1432-1238
DOI: 10.1007/bf00262901

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✦ Synopsis

We report a case of specific myocardiotoxicity due to 5 F.U. not previously described in man. A 41-year-old man was admitted to the ICU for heart and renal failure, appearing 24 h after 5 days treatment with 5 F.U. and cis-platinum. Dopamine was necessary to maintain blood pressure. Two-D echocardiography and a right heart catheterisation confirmed the alteration of myocardial contractility. After 2 weeks a complete cardiac recovery occurred.

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