Myocardial T mapping free of distortion using susceptibility-weighted fast spin-echo imaging: A feasibility study at 1.5 T and 3.0 T

✍ Scribed by Uwe Heinrichs; Jane F. Utting; Tobias Frauenrath; Fabian Hezel; Gabriele A. Krombach; Michael A.J. Hodenius; Sebastian Kozerke; Thoralf Niendorf

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 762 KB
• Volume: 62
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.22054

✦ Synopsis

Abstract

This study demonstrates the feasibility of applying free‐breathing, cardiac‐gated, susceptibility‐weighted fast spin‐echo imaging together with black blood preparation and navigator‐gated respiratory motion compensation for anatomically accurate T mapping of the heart. First, T maps are presented for oil phantoms without and with respiratory motion emulation (T = (22.1 ± 1.7) ms at 1.5 T and T = (22.65 ± 0.89) ms at 3.0 T). T relaxometry of a ferrofluid revealed relaxivities of R = (477.9 ± 17) mM^−1^s^−1^ and R = (449.6 ± 13) mM^−1^s^−1^ for UFLARE and multiecho gradient‐echo imaging at 1.5 T. For inferoseptal myocardial regions mean T values of 29.9 ± 6.6 ms (1.5 T) and 22.3 ± 4.8 ms (3.0 T) were estimated. For posterior myocardial areas close to the vena cava T‐values of 24.0 ± 6.4 ms (1.5 T) and 15.4 ± 1.8 ms (3.0 T) were observed. The merits and limitations of the proposed approach are discussed and its implications for cardiac and vascular T‐mapping are considered. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc.