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Myeloproliferative disorders with coexisting BCR-ABL translocation and JAK2V617F mutation

✍ Scribed by Go, R S

Book ID
110058335
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
57 KB
Volume
21
Category
Article
ISSN
0887-6924

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The V617F JAK2 mutation and the myeloproliferative disorders
✍ Melanie J Percy; Mary Frances McMullin 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 70 KB

## Abstract The discovery this year of a single mutation in the Janus Kinase (__JAK__)‐2 gene in a high percentage of cases of polycythaemia vera (PV), essential thrombocythaemia (ET) and myelofibrosis suggests that it maybe the underlying molecular mechanism for these disorders. Different approach