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Myelofibrosis with massive hepatosplenomegaly and osteolytic bone lesions

✍ Scribed by Ginger M. Merry; Paul B. Aronowitz

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 126 KB
Volume: 5
Category: Article
ISSN: 1553-5592
DOI: 10.1002/jhm.459

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✦ Synopsis

An 83-year-old man with a 7-year history of myelofibrosis presented to the hospital with progressive weakness and fatigue, which resulted in him tripping and falling onto his left hand and arm 1 day prior to admission. His past medical history was significant for transfusion-dependent anemia and hypertension. His current treatment regimen for myelofibrosis included thalidomide and darbopoetin alfa.

Physical examination revealed a pale and edematous man who was holding his injured arm to his chest, but in no distress. He had massive hepatosplenomegaly (Figure 1

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