Osteolytic Lesions in the Craniofacial Skeleton of a Patient with Extrapulmonary Sarcoidosis

✍ Scribed by Richard J. Wright; Bryan T. Ambro

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 449 KB
• Volume: 119
• Category: Article
• ISSN: 0023-852X
• DOI: 10.1002/lary.20431

✦ Synopsis

Case report: A 52 year old African American woman with a history of pulmonary sarcoidosis and non-compliance with her medical management presents to the otolaryngology clinic complaining of nasal obstruction, crusting, and epistaxis. On exam she had significant nasal crusting, friable mucosa with a nodular appearance, non-tender area of erythema of the anterior hard palate, and cutaneous lesions consistent with sarcoidosis. A non-contrast maxillofacial CT revealed osteolytic lesions in the pre-maxilla, greater wing of the sphenoid bone, and the parietal bone. Biopsies were performed of the middle turbinate, the premaxilla, and a cutaneous lesion. All biopsies revealed non-caseating granuloma, consistent with sarcoidosis. The patient was referred to rheumatology and aggressive combination medical therapy was initiated.