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Myelodysplastic syndrome accompanied by basophilia and eosinophilia with t(5;12)(q31;p13)

โœ Scribed by Yukitaka Katsura; Kazumi Suzukawa; Toru Nanmoku; Noriko Nemoto; Takayuki Machino; Naoshi Obara; Yasushi Okoshi; Harumi Yamamoto Mukai; Yuichi Hasegawa; Hiroshi Kojima; Yasushi Kawakami; Toshiro Nagasawa

Book ID
113513175
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
191 KB
Volume
178
Category
Article
ISSN
0165-4608

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Fusion of TEL/ETV6 to a novel ACS2 in my
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We identified a novel human long fatty acyl CoA synthetase 2 gene, ACS2, as a new ETV6 fusion partner gene in a recurrent t(5;12)(q31;p13) translocation in a patient with refractory anemia with excess blasts (RAEB) with basophilia, a patient with acute myelogenous leukemia (AML) with eosinophilia, a

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A 49-year-old woman patient with atypical myelodysplastic syndrome (MDS) showing a der(3)t(3;12)(q21;p13), and der(12)t(3; 12)(q21;p13)inv(3)(q21q26) as an acquired chromosomal abnormality in the bone marrow is described. The chromosomal breakpoints of the presented complex aberration with combinati