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Myelin basic protein intramolecular spreading without disease progression in a patient with multiple sclerosis

✍ Scribed by G. Ristori; F. Giubilei; D. Giunti; A. Perna; C. Gasperini; C. Buttinelli; M. Salvetti; A. Uccelli


Book ID
114137209
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
114 KB
Volume
110
Category
Article
ISSN
0165-5728

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Previous studies from our laboratory showed the development of circulating T lymphocytes sensitized to myelin basic protein (MBP) in guinea pigs challenged with MBP. Also, lymphocytes sensitized to MBP were found in patients with multiple sclerosis (MS). In this report, we describe the kinetics of M