Mycotoxin effects on in vitro preimplantation embryo development
β Scribed by Peter C. Svalander; Matts Olovsson; Paul V. Holmes
- Publisher
- Springer US
- Year
- 1994
- Tongue
- English
- Weight
- 505 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1573-7330
No coin nor oath required. For personal study only.
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## Abstract The optimal oxygen tension for development of preimplantation mouse embryos to the blastocyst stage in vitro was found to be between 2.5% and 5%. Oneβ and twoβcell embryos had a more sharply defined range of oxygen tension capable of supporting development than 8βcell and morula stages.
The developing use of in vitro fertilization (IVF) as a human clinical procedure has prompted the exploitation of nonhuman primates to assess the chromosomal and biochemical normality of embryos produced by IVF. Of 1995 oocytes recovered from squirrel monkeys, 628 (31.5%) matured and 339 (54.0%) fer