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Mutations of the MEN1 tumor suppressor gene in sporadic pituitary tumors

โœ Scribed by Chen Wenbin; Akio Asai; Akira Teramoto; Naoko Sanno; Takaaki Kirino


Book ID
117469476
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
139 KB
Volume
142
Category
Article
ISSN
0304-3835

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Somatic mutations of the PTEN tumor supp
โœ Naomi Halachmi; Sarel Halachmi; Ella Evron; Paul Cairns; Kenji Okami; Motoyasu S ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 113 KB ๐Ÿ‘ 3 views

The PTEN (MMAC1/TEP1) tumor suppressor gene was recently isolated and mapped to human chromosome band 10q23. Homozygous deletions and mutations of PTEN were observed in cell lines and sporadic cancers of the breast, kidney, and central nervous system. Germline mutations in PTEN were recently found i