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Mutations in X region have little impact on response to interferon therapy for chronic hepatitis B

✍ Scribed by Charles Hannoun; Kim Krogsgaard; Peter Horal; Magnus Lindh


Book ID
118565331
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
100 KB
Volume
36
Category
Article
ISSN
0168-8278

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Mutations in the X region and core promo
✍ Charles Hannoun; Peter Horal; Kim Krogsgaard; Magnus Lindh πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 204 KB

## Abstract Therapy for chronic hepatitis B with interferon‐α (IFN) may result in viral clearance and hepatitis B e seroconversion in 30–40% of patients. It is still unclear whether viral genetic variability influences response rates. However, certain core promoter mutations were recently associate