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Mutations in the SMAD4/DPC4 Gene in Juvenile Polyposis

โœ Scribed by Howe, J. R.

Book ID
121159483
Publisher
American Association for the Advancement of Science
Year
1998
Tongue
English
Weight
329 KB
Volume
280
Category
Article
ISSN
0036-8075

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Juvenile polyposis (JP) is a dominantly inherited condition characterized by the development of multiple hamartomatous tumors, juvenile polyps, in the gastrointestinal tract. The aim of this study was to clarify the role of SMAD4 in JP. DNA from four unrelated JP kindreds and three sporadic JP cases