✦ LIBER ✦

Mutations of the DPC4/Smad4 gene in neuroendocrine pancreatic tumors

✍ Scribed by Ramaswamy, Annette; Bastian, Daniel; Galehdari, Hamid; Barth, Peter; Schmiegel, Wolff; Simon, Babette; Rothmund, Matthias; Bartsch, Detlef; Hahn, Stephan A; Danichevski, Kirill D

Book ID: 110062023
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 158 KB
Volume: 18
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1202585

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Comparative mutational analysis of DPC4

Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas

✍ MacGrogan, Donal; Pegram, Mark; Slamon, Dennis; Bookstein, Robert 📂 Article 📅 1997 🏛 Nature Publishing Group 🌐 English ⚖ 351 KB

Loss of chromosome 18q and DPC4 (Smad4)

Loss of chromosome 18q and DPC4 (Smad4) mutations in appendiceal adenocarcinomas

✍ Maru, Dipen; Wu, Tsung-Teh; Canada, Amanda; Houlihan, Patrick S; Hamilton, Stanl 📂 Article 📅 2004 🏛 Nature Publishing Group 🌐 English ⚖ 258 KB

Expression of DPC4/Smad4 gene in stone-c

Expression of DPC4/Smad4 gene in stone-containing intrahepatic bile duct

✍ King-Teh Lee; Wen-Tsan Chang; Shen-Nien Wang; Shih-Chang Chuang; Chee-Yin Chai; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 193 KB

Haploid loss of the tumor suppressor Sma

Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice

✍ Xu, Xiaoling; Brodie, Steven G; Yang, Xiao; Im, Young-Hyuck; Parks, W Tony; Chen 📂 Article 📅 2000 🏛 Nature Publishing Group 🌐 English ⚖ 621 KB

Germline mutations of the dpc4 gene in K

Germline mutations of the dpc4 gene in Korean juvenile polyposis patients

✍ Il-Jin Kim; Ja-Lok Ku; Kyong-Ah Yoon; Seung Chul Heo; Seung-Yong Jeong; Hyo Seon 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 85 KB 👁 2 views

Juvenile polyposis is an uncommon condition characterized by the development of multiple (usually more than 5) juvenile polyps in the gastrointestinal tract, especially in the colon. This disease usually occurs during childhood, and is inherited in an autosomal dominant fashion. It has been suggeste

Homozygous deletions inactivate DCC, but

Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers

✍ Werner Hilgers; Jason J. Song; Marianne Haye; Ralph R. Hruban; Scott E. Kern; Er 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 88 KB

Loss of heterozygosity (LOH) of chromosome arm 18q is frequent in gastrointestinal cancers. Over 90% of pancreatic carcinomas have 18q LOH. Bi-allelic inactivation of the MADH4/DPC4/SMAD4 gene at 18q21.1 is seen in about half of pancreatic carcinomas with 18q LOH. In the remaining tumors with 18q LO