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Mutations in the lungs of gpt delta transgenic mice following inhalation of diesel exhaust

โœ Scribed by Akiko H. Hashimoto; Kimiko Amanuma; Kyoko Hiyoshi; Yoshiki Sugawara; Sataro Goto; Rie Yanagisawa; Hirohisa Takano; Ken-ichi Masumura; Takehiko Nohmi; Yasunobu Aoki

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
183 KB
Volume
48
Category
Article
ISSN
0893-6692

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Ultraviolet light B (UVB)-induced mutagenesis was studied in gpt delta transgenic mice, which contain the EG10 shuttle vector as a transgene. The mice were exposed to UVB at single doses of 0.3, 0.5, 1.0, 1.5, and 2.0 kJ/m 2 . At 4 weeks after irradiation, the mutant frequencies (MF) of the gpt gene