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Mutations in the interferon sensitivity-determining region (nonstructural 5A amino acid 2209–2248) in patients with hepatitis C-1b infection and correlating response to combined therapy of pegylated interferon and ribavirin

✍ Scribed by Y.-H. YEN; C.-H. HUNG; T.-H. HU; C.-H. CHEN; C.-M. WU; J.-H. WANG; S.-N. LU; C.-M. LEE

Book ID: 108605189
Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 123 KB
Volume: 27
Category: Article
ISSN: 0269-2813
DOI: 10.1111/j.1365-2036.2007.03560.x

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of patients with a high likelihood of response to IFN-b. In chronic hepatitis C virus (HCV) infection, geno-(HEPATOLOGY 1997;25:750-753.) types other than genotype 1b of HCV (HCV-1b) and low serum HCV-RNA levels are known to be associated with favorable outcome of interferon alfa (IFN-a) therapy. In