Mutations in the core and NS5A region of hepatitis C virus genotype 1b and correlation with response to pegylated-interferon-alpha 2b and ribavirin combination therapy
✍ Scribed by K. Hayashi; Y. Katano; M. Ishigami; A. Itoh; Y. Hirooka; I. Nakano; F. Urano; K. Yoshioka; H. Toyoda; T. Kumada; H. Goto
- Book ID
- 108886450
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 87 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1352-0504
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Hepatitis C virus (HCV) genotype 1a is rare in Japanese patients and the clinical characteristics of this genotype remain unclear. The interferon (IFN) sensitivity‐determining region (ISDR) and single‐nucleotide polymorphisms (SNPs) of interleukin‐28B (IL28B) among patients with HCV gen
## Abstract The interferon sensitivity‐determining region (ISDR) is thought to be inhibited by the double‐stranded RNA‐dependent protein kinase (PKR). Several studies have reported a relationship between the ISDR and interferon (IFN) responsiveness. However, this relationship is controversial. The