Metabolism of 2-acetylaminofluorene in t
β
Dr. Robert H. Heflich; Daniel A. Casciano; Dr. Zhou Zhuo; Dr. Zora DjuriΔ; Nancy
π
Article
π
1988
π
John Wiley and Sons
π
English
β 948 KB
Chinese hamster ovary (CHO) cells were exposed to 2-acetylaminofluorene (2-AAF) and 2-aminofluorene (2-AF), and several of their N-oxidized metabolites in order to study the mechanisms by which arylamides and arylamines produce mutations in mammalian cells. The number of mutations induced at the hyp