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Effects of metabolic inhibitors on cell lethality and mutation induction in Chinese hamster cells. I. Inhibitors of de novo purine synthesis and a comparison with the effects of caffeine

โœ Scribed by S. McMillan; M. Fox


Book ID
113136281
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
900 KB
Volume
36
Category
Article
ISSN
0009-2797

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โœ Oscar A. Scornik ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 621 KB

In the absence of serum and amino acids, cultured Chinese Hamster Ovary cells released to the medium two thirds of the leucine produced by protein degradation. Because protein synthesis requires all the amino acids, the loss of leucine implies incomplete reincorporation of the other amino acids as w