Effect of inhibitors of RNA and protein synthesis on the course of mitosis in a synchronized culture of Chinese hamster cells
โ Scribed by L. S. Strochkova
- Publisher
- Springer US
- Year
- 1978
- Tongue
- English
- Weight
- 464 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0007-4888
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In the absence of serum and amino acids, cultured Chinese Hamster Ovary cells released to the medium two thirds of the leucine produced by protein degradation. Because protein synthesis requires all the amino acids, the loss of leucine implies incomplete reincorporation of the other amino acids as w
## Abstract The frequency of mutations induced by ethyl methane sulfonate was compared in a pseudodiploid Chinese hamster cell strain and in a tetraploid substrain derived from it. The frequency of reverse mutations from glycine auxotrophy to glycine independence was similar in the two strains, as
## Abstract V79โ8 cells lack a measurable G1 interval under normal growth conditions. We found that partial inhibition of protein synthesis using low levels of cycloheximide (0.05 ฮผ/ml) could induce a measurable G1 in these cells without any significant effects on S, G2, or M. In view of these find