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Mutations in LRP5 and SOST are a rare cause of high bone mass in the general population

✍ Scribed by E.L. Duncan; C.L. Gregson⁎; K. Addison; M. Brugmans; J.J. Pointon; L.H. Appleton; J.H. Tobias; M.A. Brown

Book ID
116321681
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
69 KB
Volume
44
Category
Article
ISSN
8756-3282

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## Abstract Patients with an activation mutation of the __Lrp5__ gene exhibit high bone mass (HBM). Limited information is available regarding compartment‐specific changes in bone. The relationship between the phenotype and serum serotonin is not well documented. To evaluate bone, serotonin, and bo