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Mutations Affecting the Sensitivity of the Influenza Virus Neuraminidase to 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic Acid

โœ Scribed by Hideo Goto; Richard C Bethell; Yoshihiro Kawaoka


Book ID
112271758
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
112 KB
Volume
238
Category
Article
ISSN
0042-6822

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The biochemistry and synthesis of sialidase inhibitors, in particular influenza virus sialidase inhibitors, has been of great interest to us [1][2][3]. The synthesis of a number of S-acetamido-2,6-anhydro-3,5-dideoxy-o-glycero-o-galacto-non-2-enonic acid (Neu5Ac2en, 1) analogues has received conside