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Mutations affecting ligand specificity of the G-protein-coupled receptor for the Saccharomyces cerevisiae tridecapeptide pheromone

โœ Scribed by Michael G. Abel; Byung-Kwon Lee; Fred Naider; Jeffrey M. Becker


Book ID
117351044
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
248 KB
Volume
1448
Category
Article
ISSN
0167-4889

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Peptides representing both loop and the sixth transmembrane regions of the โฃ-factor receptor of Saccharomyces cerevisiae were synthesized by solid-phase procedures and purified to near homogeneity. CD, nmr, and modeling analysis indicated that in aqueous media the first extracellular loop peptide E1