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Mutational specificity of 2-nitro-3,4-dimethylimidazo[4,5- f ]quinoline in the lacI gene of Escherichia coli

✍ Scribed by Kosakarn, P.; Halliday, J.A.; Glickman, B.W.; Josephy, P.D.


Book ID
127211646
Publisher
Oxford University Press
Year
1993
Tongue
English
Weight
712 KB
Volume
14
Category
Article
ISSN
0143-3334

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## Abstract 2‐Amino‐3,4‐dimethylimidazo[4,5‐__f__]quinoline (MelQ), a food mutagen, induces forestomach tumors in CDF~1~ mice. We established a polymerase chain reaction (PCR)–single‐strand conformation polymorphism (SSCP) analysis system to detect mutations in the mouse __p53__ gene exons 2–10, wh