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Genotoxic activity of the N -acetylated metabolites of the food mutagens 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3, 4-dimethylimidazo[4,5-f]quinoline (MeIQ)

✍ Scribed by Brunborg, Gunnar; Holme, Jørn A.; Alexander, Jan; Becher, Georg; Hongslo, Jan K.


Book ID
121507937
Publisher
Oxford University Press
Year
1988
Tongue
English
Weight
730 KB
Volume
3
Category
Article
ISSN
0267-8357

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Mutagenic activation of 2-amino-3-methyl
✍ Jørna A. Holme; Jan Alexander; Erik Dybing 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 669 KB

The mutagenic activity of the pyrolysis products 2-amino-3-methylimidazo [4,5-J'\_~quinoline and 2-amino-3, 4-dimethylimidazo[4,5-fJ-quinoline in Salmonella typhimurium TA98 using rat intestinal and renal subcellular fractions as activation systems was approximately 1 and 5 revertants per nmol, resp