Mutational patterns and novel mutations of BRAF gene in a large cohort of Korean patients with papillary thyroid carcinoma
β Scribed by Jung, Chan-Kwon; Im, So-Young; Kang, Yeo-Ju; Lee, Hyoungnam; Jung, Eun-Sun; Kang, Chang Suk; Bae, Ja-Seong; Choi, Yeong-Jin
- Book ID
- 115459782
- Publisher
- Mary Ann Liebert
- Year
- 2012
- Tongue
- English
- Weight
- 595 KB
- Volume
- 0
- Category
- Article
- ISSN
- 1050-7256
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## Abstract In search of tumor suppressor genes in papillary thyroid carcinoma (PTC), we previously used gene expression profiling to identify genes underexpressed in tumor compared with paired unaffected tissue. While searching for loss of heterozygosity (LOH) in genomic regions harboring candidat
## Abstract ## BACKGROUND: Although several studies undoubtedly demonstrated that __BRAF__ mutation is an important genetic event in the pathogenesis of papillary thyroid carcinoma (PTC), its prognostic significance and correlation with less differentiated states remains unclear. It has been sugge