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Mutational analysis ofRac2in gliomas

✍ Scribed by Ahmed Idbaih; Sophie Paris; Blandine Boisselier; Yannick Marie; Marc Sanson; Joëlle Thillet; Khê Hoang-Xuan; Jean-Yves Delattre


Book ID
106480926
Publisher
Springer US
Year
2008
Tongue
English
Weight
164 KB
Volume
87
Category
Article
ISSN
0167-594X

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The PTEN gene, recently identified on chromosome 10q23, has been proposed to be a candidate tumor suppressor gene inactivated in multiple cancers including glial tumors. We investigated 47 glioblastomas (GBM), 14 anaplastic astrocytomas (AA), 6 non-pilocytic low-grade astrocytomas (LGA), 21 low-grad