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Analysis of TP53 mutations in human malignant gliomas

✍ Scribed by Norman, Sylvia; Scheck, Adrienne; Braman, Jeff


Book ID
109830480
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
83 KB
Volume
27
Category
Article
ISSN
1061-4036

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A detailed analysis of p53 (TP53) mutations involving the 42 CpG dinucleotides was performed to gain greater insight into the mutational mechanism leading to specific selection of these mutations. Although the majority of these CpG dinucleotides have been found to be mutated in cancer cells, the het