✦ LIBER ✦

Mutational analysis of transforming growth factor-beta receptor type II and Smad3 tumor suppressor genes in prolactinomas

✍ Scribed by Hidetoshi Ikeda

Publisher: Springer Japan
Year: 2006
Tongue: English
Weight: 329 KB
Volume: 23
Category: Article
ISSN: 1433-7398
DOI: 10.1007/s10014-006-0196-7

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Microsatellite instability and gene muta

Microsatellite instability and gene mutations in transforming growth factor-beta type II receptor are absent in small bowel carcinoid tumors

✍ Mark Kidd; Geeta Eick; Michael D. Shapiro; Robert L. Camp; Shrikant M. Mane; Irv 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 350 KB

Gene mutation of transforming growth fac

Gene mutation of transforming growth factor β1 type II receptor in hepatocellular carcinoma

✍ Keiko Furuta; Sachiko Misao; Kiyoshi Takahashi; Tsuneaki Tagaya; Yoshitaka Fukuz 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 146 KB 👁 1 views

Alteration of transforming growth factor beta1 (TGF-beta1) type II receptor (RII) appears to cause unresponsiveness to TGF-beta1 in tumorigenic cells. Defect in the mononucleotide repeat sequence, i.e., poly A region of TGF-beta1RII gene has been reported to be related to replication error-positive

Mutations of the transforming growth fac

Mutations of the transforming growth factor β type II receptor gene and microsatellite instability in gastric cancer

✍ Masayuki Ohue; Naohiro Tomita; Takushi Monden; Yasuo Miyoshi; Tadashi Ohnishi; H 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 517 KB

Forty-three sporadic gastric cancers were analyzed with regard to whether mutations of simple repeated sequences in the transforming growth factor fi type II receptor ( T p -I / ) gene are associated with microsatellite instability (MSI) and gastric carcinogenesis. In 12 ofthe 43 cancers (28%), MSI

Enhanced tumorigenesis and reduced trans

Enhanced tumorigenesis and reduced transforming growth factor-β type II receptor in lung tumors from mice with reduced gene dosage of transforming growth factor-β1

✍ Yang Kang; Jennifer M. Mariano; Jerry Angdisen; Terry W. Moody; Bhalchandra A. D 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 306 KB 👁 1 views

To elucidate the role of transforming growth factor-beta1 (TGF-beta1) and the TGF-beta type II receptor (TGF-beta RII) as tumor-suppressor genes in lung carcinogenesis, we mated C57BL/6 mice heterozygous (HT) for deletion of the TGF-beta1 gene with A/J mice to produce AJBL6 TGF-beta1 HT progeny and

Interleukin-1β impairment of transformin

Interleukin-1β impairment of transforming growth factor β1 signaling by DOWN-REGULATION of transforming growth factor β receptor type II and up-regulation of Smad7 in human articular chondrocytes

✍ C. Baugé; F. Legendre; S. Leclercq; J. M. Elissalde; J. P. Pujol; P. Galéra; K. 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 680 KB

Novel inactivating mutations of transfor

Novel inactivating mutations of transforming growth factor-β type I receptor gene in head-and-neck cancer metastases

✍ Taiping Chen; Wu Yan; Rebecca G. Wells; David L. Rimm; Jennifer McNiff; David Le 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 263 KB

Carcinoma cell lines are frequently refractory to transforming growth factor-beta (TGF beta)-mediated cell cycle arrest. Whether and how TGF beta signaling is disrupted in the majority of human tumors, however, remains unclear. To investigate whether TGF beta signaling might be disrupted by inactiva