Forty-three sporadic gastric cancers were analyzed with regard to whether mutations of simple repeated sequences in the transforming growth factor fi type II receptor ( T p -I / ) gene are associated with microsatellite instability (MSI) and gastric carcinogenesis. In 12 ofthe 43 cancers (28%), MSI
โฆ LIBER โฆ
Microsatellite instability and gene mutations in transforming growth factor-beta type II receptor are absent in small bowel carcinoid tumors
โ Scribed by Mark Kidd; Geeta Eick; Michael D. Shapiro; Robert L. Camp; Shrikant M. Mane; Irvin M. Modlin
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 350 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0008-543X
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In this study, we determined the incidence of microsatellite instability (MIN) in pancreatic adenocarcinoma and determined whether MIN might target, for mutations, the simple nucleotide repeats of the transforming growth factor โค type II receptor (TGFBR2) gene. Forty-eight surgically resected pancre