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Mutational analysis of the p15 and p16 genes in acute leukaemias

✍ Scribed by H. Sill; R. C. T. Aguiar; H. Schmidt; A. Hochhaus; J. M. Goldman; N. C. P. Cross

Book ID
114424984
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
95 KB
Volume
92
Category
Article
ISSN
0007-1048

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Neuroblastoma is one of the most frequent tumors in infancy. We analyzed 26 neuroblastomas, two ganglioneuromas, and a neuroblastoma metastasis for mutations and homozygous deletions of the p16 (or MTS1 or CDKN2) gene by means of the polymerase chain reaction (PCR) in combination with the single-str