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Mutational analysis of the human cyclin-dependent kinase inhibitor p27kip1in primary breast carcinomas

✍ Scribed by Ferrando, AdolfoA.; Balb�n, Milagros; Pend�s, AlbertoM.; Vizoso, Francisco; Velasco, Gloria; L�pez-Ot�n, Carlos


Book ID
118771716
Publisher
Springer
Year
1996
Tongue
English
Weight
501 KB
Volume
97
Category
Article
ISSN
0340-6717

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## Background and objectives: P27kip1 (p27) plays an important role as a negative regulator of cell cycle-dependent kinase activity during progression of the cell cycle. the most important prognosticator of breast cancer is nodal status, and the aim of this study was to determine the prognostic imp