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Mutational analysis of TARDBP in Parkinson's disease

✍ Scribed by van Blitterswijk, Marka; van Es, Michael A.; Verbaan, Dagmar; van Hilten, Jacobus J.; Scheffer, Hans; van de Warrenburg, Bart P.; Veldink, Jan H.; van den Berg, Leonard H.


Book ID
123234109
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
114 KB
Volume
34
Category
Article
ISSN
0197-4580

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## Abstract We performed sequence analysis of all the exons and exon–intron boundaries in familial and young‐onset Parkinson's disease (PD) in an Asian cohort. None of the patients carried any pathogenic mutations in the Nurr1 gene. We demonstrated a 5 to 10% prevalence of the intron 7 +33 Cβ†’T vari