𝔖 Bobbio Scriptorium
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Mutational Analysis of Metallo-β-lactamase CcrA from Bacteroides fragilis †

✍ Scribed by Yanchak, Margaret P.; Taylor, Rebecca A.; Crowder, Michael W.


Book ID
126223606
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
168 KB
Volume
39
Category
Article
ISSN
0006-2960

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## Abstract The metallo‐β‐lactamases require zinc or cadmium for hydrolyzing β‐lactam antibiotics and are inhibited by mercurial compounds. To date, there are no clinically useful inhibitors of this class of enzymes. The crystal structure of the Zn^2+^‐bound enzyme from __Bacteroides fragilis__ con