## Abstract Four genes responsible for recessively inherited forms of Parkinson's disease (PD) have been identified, including the recently discovered __ATP13A2__ (__PARK9__) gene. Our objective was to investigate the role of this gene in a large cohort of PD patients and controls. We extensively s
Mutational analysis of GIGYF2, ATP13A2 and GBA genes in Brazilian patients with early-onset Parkinson's disease
✍ Scribed by Adriana Vaz dos Santos; Cristiane Pinheiro Pestana; Karen Rafaella da Silva Diniz; Mário Campos; Cláudia Bueno Abdalla-Carvalho; Ana Lúcia Zuma de Rosso; João Santos Pereira; Denise Hack Nicaretta; William Luciano de Carvalho; Jussara Mendonça dos Santos; Cíntia Barros Santos-Rebouças; Márcia Mattos Gonçalves Pimentel
- Book ID
- 116772608
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 144 KB
- Volume
- 485
- Category
- Article
- ISSN
- 0304-3940
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## Abstract Autosomal recessive early‐onset Parkinsonism (AREP) has been associated with mutations in the __Parkin__, __PINK1__, __DJ‐1__, and __ATP13A2__ genes. We studied the prevalence of mutations in all four genes in 29 Chinese unrelated families with AREP using direct sequencing analysis and