Mutation spectrum of RB1 gene in Korean bilateral retinoblastoma patients using direct sequencing and gene dosage analysis
✍ Scribed by SH Seo; HS Ahn; YS Yu; HJ Kang; KD Park; SI Cho; JS Park; YJ Hyun; JY Kim; M-W Seong; SS Park
- Book ID
- 119839686
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 529 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0009-9163
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## Communicated by Daniel F. Schorderet Constitutional mutations in the RB1 gene predispose to retinoblastoma development. Hence genetic screening of retinoblastoma patients and relatives is important for genetic counseling purposes. In addition, RB1 gene mutation studies may help decipher the mol
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