Mutation screening of the HTR2B gene in patients with Tourette syndrome
β Scribed by Yi Guo; Xiong Deng; Joseph Jankovic; Linyan Su; Jie Zhang; Weidong Le; Hongbo Xu; Zuocheng Yang; Jinsong Tang; Shoujin Kuang; Hao Deng
- Book ID
- 118165893
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 179 KB
- Volume
- 526
- Category
- Article
- ISSN
- 0304-3940
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We report a single stranded conformational polymorphism (SSCP) analysis of the coding region of the dopamine D1 receptor (DRD1) in Tourette's syndrome (n = 50) and control (n = 50) subjects. Tourette's syndrome populations with comorbidity for attention deficit-hyperactivity disorder (AD-HD) (n = 35
Tourette syndrome (TS) is a complex inherited neuropsychiatric disorder characterized by multiple motor and phonic tics. Involvement of central norepinephrine mechanisms is suggested by central norepinephrinic hyperactivity in patients with TS and by the therapeutic effects of the presynaptic β£ 2 -a