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Mutation of lysine 1370 in full-length human α2-macroglobulin blocks binding to the low density lipoprotein receptor-related protein-1

✍ Scribed by Sanja Arandjelovic; Brian D. Hall; Steven L. Gonias

Book ID
116177334
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
350 KB
Volume
438
Category
Article
ISSN
0003-9861

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✍ Birkenmeier, Gerd; Usbeck, Elke; Schäfer, Angelika; Otto, Andreas; Glander, Hans 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 348 KB 👁 1 views

The aim of this study was to identify the proteolytic activity which triggers the transformation of human ␣2-macroglobulin (␣2-M) in seminal fluid and its binding to its receptor. METHODS. Measurement of the concentrations of total and transformed ␣2-M in seminal fluid was accomplished by ELISA. Zym