Low density lipoprotein receptor-related protein (LRP) participates in the uptake and degradation of several ligands implicated in neuronal pathophysiology including apolipoprotein E (apoE), activated ␣ 2 -macroglobulin (␣ 2 M\*) and -amyloid precursor protein (APP). The receptor is expressed in a
Different expression of the α2-macroglobulin receptor/low-density lipoprotein receptor-related protein in human keratinocytes and fibroblasts
✍ Scribed by G. Birkenmeier; Katja Heidrich; Christine Gläser; Katrin Handschug; Eva-Maria Fabricius; Roman Frank; Dieter Reissig
- Publisher
- Springer-Verlag
- Year
- 1998
- Tongue
- English
- Weight
- 416 KB
- Volume
- 290
- Category
- Article
- ISSN
- 0340-3696
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The aim of this study was to identify the proteolytic activity which triggers the transformation of human ␣2-macroglobulin (␣2-M) in seminal fluid and its binding to its receptor. METHODS. Measurement of the concentrations of total and transformed ␣2-M in seminal fluid was accomplished by ELISA. Zym
## Abstract The aim of this study was to investigate the activation of the Wnt/β‐catenin pathway in osteoarthritis and the role of low‐density lipoprotein receptor‐related protein 5 (LRP5) in human osteoarthritic chondrocytes. The influence of 1,25(OH)~2~D~3~ on the expression of the __LRP5__ gene
Human pregnancy zone protein (PZP) is a major pregnancy-associated plasma protein closely related to human alpha(2)-macroglobulin (alpha(2)M). It has been demonstrated that monoamine-activated forms of human and rat alpha(2)M and rat alpha(1)M can bind to TrkA and, respectively, inhibit and stimulat
␣ 2 -Macroglobulin receptor/low-density lipoprotein receptor-related protein is a multifunctional cell surface receptor known to bind and internalize a large number of ligands. ␣ 2 -Macroglobulin receptor-associated protein acts as an intracellular ''chaperone'' for this receptor, and it has been sh