Multiple, diverse senile plaque–associated proteins are ligands of an apolipoprotein e receptor, the α2-macroglobulin receptor/low-density-lipoprotein receptor—related protein

Low-density lipoprotein receptor-related

Low-density lipoprotein receptor-related protein mediates in PC12 cell cultures the inhibition of nerve growth factor-promoted neurite outgrowth by pregnancy zone protein and α2-macroglobulin

✍ Gustavo A. Chiabrando; María C. Sánchez; Erin L. Skornicka; Peter H. Koo 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 275 KB 👁 1 views

Human pregnancy zone protein (PZP) is a major pregnancy-associated plasma protein closely related to human alpha(2)-macroglobulin (alpha(2)M). It has been demonstrated that monoamine-activated forms of human and rat alpha(2)M and rat alpha(1)M can bind to TrkA and, respectively, inhibit and stimulat