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Mutation of amino acid 475 of rat organic cation transporter 2 (rOCT2) impairs organic cation transport

✍ Scribed by Andrew Bahn; Yohannes Hagos; Tanja Rudolph; Gerhard Burckhardt


Book ID
116308279
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
197 KB
Volume
86
Category
Article
ISSN
0300-9084

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## Background: In rat kidneys, the organic ion transporters roct1, roct2, roat1 and roat3 are considered to mediate the basolateral uptake of various ionic compounds. however, their changes in chronic renal failure (crf) are poorly understood. the present study examined the renal handling of organi