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Mutation in the β amyloid precursor protein gene and schizophrenia

✍ Scribed by Markus M. Nöthen; Jeanette Erdmann; Peter Propping; Mario Lanczik; Marcella Rietschel; Judith Körner; Wolfgang Maier; Margot Albus; Martha A. Ert; Dieter B. Wildenauer


Book ID
118856415
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
84 KB
Volume
34
Category
Article
ISSN
0006-3223

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A novel mutation in the β-protein coding
✍ Milagros Balbín; Magnus Abrahamson; Lars Gustafson; Karin Nilsson; Arne Brun; An 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 329 KB

A novel mutation, a C to T transition at base pair 2124 in exon 17 of the amyloid beta-protein precursor (APP) gene, has been identified by direct sequencing of amplified DNA from two Alzheimer's disease (AD) patients. A simple oligonucleotide-hybridization procedure was developed to allow populatio