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Mutation at the adenine phosphoribosyl transferase locus in Friend leukaemia cells

โœ Scribed by P. Ward; P.G. McKenna


Book ID
113250813
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
69 KB
Volume
130
Category
Article
ISSN
0165-1161

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## Communicated by Steve S. Sommer Hypoxanthine phosphoribosyl transferase (HPRT, also known as HGPRT) is an often-used genetic marker in eukaryotic cells. The gene is conserved from bacteria to human, with retained catalytic activity, although substrate specificity may have changed, and the enzym