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Induction of mutations at the hypoxanthine phosphoribosyl transferase (HPRT) locus in AHH-1 human lymphoblastoid cells

โœ Scribed by Suzane M. Morris; Olen E. Dimon; K. Barry Delclos; James J. Chen; Daniel A. Casciano


Book ID
113194484
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
840 KB
Volume
310
Category
Article
ISSN
0027-5107

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## Communicated by Steve S. Sommer Hypoxanthine phosphoribosyl transferase (HPRT, also known as HGPRT) is an often-used genetic marker in eukaryotic cells. The gene is conserved from bacteria to human, with retained catalytic activity, although substrate specificity may have changed, and the enzym