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Mutation and expression analysis of the putative prostate tumour-suppressor gene PTEN

✍ Scribed by Gray, IC; Stewart, LMD; Phillips, SMA; Hamilton, JA; Gray, NE; Watson, GJ; Spurr, NK; Snary, D

Book ID: 109838673
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 830 KB
Volume: 78
Category: Article
ISSN: 0007-0920
DOI: 10.1038/bjc.1998.674

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BACKGROUND. p53 is the most highly mutated tumor suppressor gene in human cancers. Recently, p73, a first homologue of p53, was identified and considered to be an imprinted tumor suppressor gene. Thus, we analyzed the possible role of p73 in human prostate cancers. METHODS. We investigated the expre