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Mutation and association analysis of the interferon regulatory factor 2 gene (IRF2) with atopic dermatitis

✍ Scribed by Y. Nishio; E. Noguchi; S. Ito; E. Ichikawa; Y. Umebayashi; F. Otsuka; T. Arinami


Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
63 KB
Volume
46
Category
Article
ISSN
1435-232X

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IRF2 is a transcription factor, possessing oncogenic potential, responsible for both the repression of growth-inhibiting genes (interferon) and the activation of cell cycle-regulated genes (histone H4). Surprisingly little is known about the post-translational modification of this factor. In this st