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Mutation analysis of transforming growth factor beta type I receptor, type II receptor, Smad2, Smad4, Smad6 and Smad7 in hepatocellular carcinoma

✍ Scribed by Kawate, Susumu; Ohwada, Susumu; Kunihiro, Hamada; Koyama, Toru; Sakamoto, Ichiro; Yoshinari, Daisuke; Kasahara, Mureo; Tomizawa, Naoki; Kawashima, Yoshiyuki; Takeyoshi, Izumi; Morishita, Yasuo


Book ID
122039965
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
179 KB
Volume
118
Category
Article
ISSN
0016-5085

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Gene mutation of transforming growth fac
✍ Keiko Furuta; Sachiko Misao; Kiyoshi Takahashi; Tsuneaki Tagaya; Yoshitaka Fukuz πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 146 KB πŸ‘ 1 views

Alteration of transforming growth factor beta1 (TGF-beta1) type II receptor (RII) appears to cause unresponsiveness to TGF-beta1 in tumorigenic cells. Defect in the mononucleotide repeat sequence, i.e., poly A region of TGF-beta1RII gene has been reported to be related to replication error-positive