A group of 83 Spanish BC/OC families were analysed for BRCA1 germ-line mutations. Analysis of the entire coding sequence was carried out by SSCP and PTT. We identified 5 frameshift mutations: 185delAG (2 times), 189insTGTC, 1241delAC, and 5537delA and 3 missense mutations in BRCA1: 330A G G, 1240C G
✦ LIBER ✦
Mutation analysis of the BRCA2 gene in breast/ovarian cancer Spanish families: identification of two new mutations
✍ Scribed by Ana Osorio; Mercedes Robledo; Juan Manual San Román; Jose Albertos; Jesús Andrade; Ana Barabash; Javier Benı́tez
- Book ID
- 117468556
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 71 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0304-3835
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