A group of 83 Spanish BC/OC families were analysed for BRCA1 germ-line mutations. Analysis of the entire coding sequence was carried out by SSCP and PTT. We identified 5 frameshift mutations: 185delAG (2 times), 189insTGTC, 1241delAC, and 5537delA and 3 missense mutations in BRCA1: 330A G G, 1240C G
Molecular analysis of the BRCA2 gene in 16 breast/ovarian cancer Spanish families
✍ Scribed by Ana Osorio; Mercedes Robledo; Beatriz Martínez; Arancha Cebrián; Juan Manuel San Román; Jose Albertos; Francisco Lobo; Javier Benitez
- Book ID
- 110887818
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 519 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0009-9163
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