Mutation analysis in WT1 in patients with Wilms' tumors
✍ Scribed by A.C. Santos; M.L. Osório-Almeida; M.G. Boavida; J.M. Silva; A.G. t Martins; J. Cowell
- Book ID
- 119105719
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 65 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0165-4608
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A series of twenty unselected Wilms′ tumors were analysed for alterations in the __WT1__ tumor suppressor gene. The entire coding region of __WT1__ was amplified by RNA‐PCR, and then screened for mutations by single‐strand conformational polymorphism analysis (SSCP). This method was sho
We conducted a comparative study of the prevalence of gerrnline WTI mutations in patients with Wilms' tumor. Patients in Group l have familial Wilms' tumor, bilateral disease, associated urogenital anomalies, and/or second cancers. Those in Group 2 are unilateral, sporadic Wilrns' patients without o